4jba | pdb_00004jba

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Template:STRUCTURE 4jba

Crystal Structure of the Oxidized Form of MarR from E.coli

Template:ABSTRACT PUBMED 24185215

Function

[MARR_ECOLI] Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site.

About this Structure

4jba is a 2 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.

Reference

  1. Hao Z, Lou H, Zhu R, Zhu J, Zhang D, Zhao BS, Zeng S, Chen X, Chan J, He C, Chen PR. The multiple antibiotic resistance regulator MarR is a copper sensor in Escherichia coli. Nat Chem Biol. 2014 Jan;10(1):21-8. doi: 10.1038/nchembio.1380. Epub 2013 Nov 3. PMID:24185215 doi:https://dx.doi.org/10.1038/nchembio.1380

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