3pil | pdb_00003pil

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Template:STRUCTURE 3pil

Crystal structure of Mxr1 from Saccharomyces cerevisiae in reduced form

Template:ABSTRACT PUBMED 21345799

Function

[MSRA_YEAST] Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Also able to reduce dimethyl sulfoxide (DMSO) as well, with DMS as the product.

About this Structure

3pil is a 2 chain structure with sequence from Atcc 18824. Full crystallographic information is available from OCA.

Reference

  1. Ma XX, Guo PC, Shi WW, Luo M, Tan XF, Chen Y, Zhou CZ. Structural plasticity of the thioredoxin recognition site of yeast methionine S-sulfoxide reductase Mxr1. J Biol Chem. 2011 Apr 15;286(15):13430-7. Epub 2011 Feb 23. PMID:21345799 doi:https://dx.doi.org/10.1074/jbc.M110.205161

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