3j66 | pdb_00003j66

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Template:STRUCTURE 3j66

Arx1 pre-60S particle. This entry contains the alternative position for Rlp7.

Template:ABSTRACT PUBMED 24662372

Function

[RLP7_YEAST] Involved in the biogenesis of the 60S ribosomal subunit. May act as a specificity factor that binds precursor rRNAs and tethers the enzymes that carry out the early 5' to 3' exonucleolytic reactions that generate the mature rRNAs.[1]

About this Structure

3j66 is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  1. Leidig C, Thoms M, Holdermann I, Bradatsch B, Berninghausen O, Bange G, Sinning I, Hurt E, Beckmann R. 60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle. Nat Commun. 2014 Mar 24;5:3491. doi: 10.1038/ncomms4491. PMID:24662372 doi:https://dx.doi.org/10.1038/ncomms4491
  1. ↑ Dunbar DA, Dragon F, Lee SJ, Baserga SJ. A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis. Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13027-32. PMID:11087857 doi:https://dx.doi.org/10.1073/pnas.97.24.13027

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