4ns5 | pdb_00004ns5

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Template:STRUCTURE 4ns5

Crystal structure of human BS69 Bromo-Zinc finger-PWWP

Function

[ZMY11_HUMAN] Corepressor of transcription (Probable). May be involved in chromatin remodeling through association with several remodeling factors.[1] [2]

About this Structure

4ns5 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Wang J, Qin S, Li F, Li S, Zhang W, Peng J, Zhang Z, Gong Q, Wu J, Shi Y. Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding. Cell Res. 2014 Mar 28. doi: 10.1038/cr.2014.38. PMID:24675531 doi:https://dx.doi.org/10.1038/cr.2014.38
  1. ↑ Velasco G, Grkovic S, Ansieau S. New insights into BS69 functions. J Biol Chem. 2006 Jun 16;281(24):16546-50. Epub 2006 Mar 24. PMID:16565076 doi:https://dx.doi.org/10.1074/jbc.M600573200
  2. ↑ Masselink H, Bernards R. The adenovirus E1A binding protein BS69 is a corepressor of transcription through recruitment of N-CoR. Oncogene. 2000 Mar 16;19(12):1538-46. PMID:10734313 doi:https://dx.doi.org/10.1038/sj.onc.1203421

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