1a50 | pdb_00001a50
From Proteopedia
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUOROINDOLE PROPANOL PHOSPHATE
Template:ABSTRACT PUBMED 9548921
Function
[TRPA_SALTY] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. [TRPB_SALTY] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
About this Structure
1a50 is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar typhimurium. Full crystallographic information is available from OCA.
Reference
- Schneider TR, Gerhardt E, Lee M, Liang PH, Anderson KS, Schlichting I. Loop closure and intersubunit communication in tryptophan synthase. Biochemistry. 1998 Apr 21;37(16):5394-406. PMID:9548921 doi:https://dx.doi.org/10.1021/bi9728957
