1b4e | pdb_00001b4e
From Proteopedia
X-ray structure of 5-aminolevulinic acid dehydratase complexed with the inhibitor levulinic acid
Template:ABSTRACT PUBMED 10194344
Function
[HEM2_ECOLI] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
About this Structure
1b4e is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Erskine PT, Norton E, Cooper JB, Lambert R, Coker A, Lewis G, Spencer P, Sarwar M, Wood SP, Warren MJ, Shoolingin-Jordan PM. X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution. Biochemistry. 1999 Apr 6;38(14):4266-76. PMID:10194344 doi:10.1021/bi982137w
