1bj0 | pdb_00001bj0
From Proteopedia
TETRACYCLINE CHELATED MG2+-ION INITIATES HELIX UNWINDING FOR TET REPRESSOR INDUCTION
Template:ABSTRACT PUBMED 9890898
Function
[TETR4_ECOLI] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
About this Structure
1bj0 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Orth P, Saenger W, Hinrichs W. Tetracycline-chelated Mg2+ ion initiates helix unwinding in Tet repressor induction. Biochemistry. 1999 Jan 5;38(1):191-8. PMID:9890898 doi:10.1021/bi9816610
