4azd | pdb_00004azd

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Template:STRUCTURE 4azd

T57V mutant of aspartate decarboxylase

Template:ABSTRACT PUBMED 24699660

Function

[PAND_ECOLI] Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.[1]

About this Structure

4azd is a 2 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.

Reference

  1. Webb ME, Yorke BA, Kershaw T, Lovelock S, Lobley CM, Kilkenny ML, Smith AG, Blundell TL, Pearson AR, Abell C. Threonine 57 is required for the post-translational activation of Escherichia coli aspartate alpha-decarboxylase. Acta Crystallogr D Biol Crystallogr. 2014 Apr 1;70(Pt 4):1166-72. doi:, 10.1107/S1399004713034275. Epub 2014 Mar 21. PMID:24699660 doi:https://dx.doi.org/10.1107/S1399004713034275
  1. ↑ Cronan JE Jr. Beta-alanine synthesis in Escherichia coli. J Bacteriol. 1980 Mar;141(3):1291-7. PMID:6767707

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