1nw3 | pdb_00001nw3
From Proteopedia
Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
Function
[DOT1L_HUMAN] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
About this Structure
1nw3 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA.
See Also
Reference
- Min J, Feng Q, Li Z, Zhang Y, Xu RM. Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase. Cell. 2003 Mar 7;112(5):711-23. PMID:12628190
