1n5m | pdb_00001n5m

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Template:STRUCTURE 1n5m

Crystal structure of the mouse acetylcholinesterase-gallamine complex

Template:ABSTRACT PUBMED 12505979

Function

[ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.

About this Structure

1n5m is a 2 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

See Also

Reference

  1. Bourne Y, Taylor P, Radic Z, Marchot P. Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site. EMBO J. 2003 Jan 2;22(1):1-12. PMID:12505979 doi:https://dx.doi.org/10.1093/emboj/cdg005

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OCA