1ohv | pdb_00001ohv

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Template:STRUCTURE 1ohv

4-AMINOBUTYRATE-AMINOTRANSFERASE FROM PIG

Template:ABSTRACT PUBMED 14534310

Function

[GABT_PIG] Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.

About this Structure

1ohv is a 4 chain structure with sequence from Sus scrofa. This structure supersedes the now removed PDB entry 1gtx. Full crystallographic information is available from OCA.

Reference

  1. Storici P, De Biase D, Bossa F, Bruno S, Mozzarelli A, Peneff C, Silverman RB, Schirmer T. Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin. J Biol Chem. 2004 Jan 2;279(1):363-73. Epub 2003 Oct 8. PMID:14534310 doi:10.1074/jbc.M305884200

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