1jqa | pdb_00001jqa

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Template:STRUCTURE 1jqa

Bacillus stearothermophilus glycerol dehydrogenase complex with glycerol

Template:ABSTRACT PUBMED 11566129

Function

[GLDA_GEOSE] Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates, such as propan-1,2-diol, butan-2,3-diol, ethan-1,2-diol, and 3-mercapto-1,2-dihydroxypropane.[1]

About this Structure

1jqa is a 1 chain structure with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

  1. Ruzheinikov SN, Burke J, Sedelnikova S, Baker PJ, Taylor R, Bullough PA, Muir NM, Gore MG, Rice DW. Glycerol dehydrogenase. structure, specificity, and mechanism of a family III polyol dehydrogenase. Structure. 2001 Sep;9(9):789-802. PMID:11566129
  1. ↑ Spencer P, Bown KJ, Scawen MD, Atkinson T, Gore MG. Isolation and characterisation of the glycerol dehydrogenase from Bacillus stearothermophilus. Biochim Biophys Acta. 1989 Feb 23;994(3):270-9. PMID:2493267

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