1f7b | pdb_00001f7b

From Proteopedia
Revision as of 10:47, 16 April 2014 by OCA (talk | contribs)
Jump to navigationJump to search

Template:STRUCTURE 1f7b

CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II IN COMPLEX WITH 4-OXO-SIALIC ACID

Template:ABSTRACT PUBMED 11031117

Function

[NANA_HAEIN] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.

About this Structure

1f7b is a 2 chain structure with sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.

Reference

  1. Barbosa JA, Smith BJ, DeGori R, Ooi HC, Marcuccio SM, Campi EM, Jackson WR, Brossmer R, Sommer M, Lawrence MC. Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme. J Mol Biol. 2000 Oct 27;303(3):405-21. PMID:11031117 doi:https://dx.doi.org/10.1006/jmbi.2000.4138

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1f7b&oldid=1914587"