1jg4 | pdb_00001jg4

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Template:STRUCTURE 1jg4

Crystal Structure of L-isoaspartyl (D-aspartyl) O-methyltransferase with S-adenosylmethionine

Template:ABSTRACT PUBMED 11700066

Function

[PIMT_PYRFU] Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity).

About this Structure

1jg4 is a 1 chain structure with sequence from Pyrococcus furiosus. Full crystallographic information is available from OCA.

Reference

  1. Griffith SC, Sawaya MR, Boutz DR, Thapar N, Katz JE, Clarke S, Yeates TO. Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its L-isoaspartyl peptide substrate. J Mol Biol. 2001 Nov 9;313(5):1103-16. PMID:11700066 doi:10.1006/jmbi.2001.5095

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