1rc9 | pdb_00001rc9
From Proteopedia
Crystal Structure of Stecrisp, a Member of CRISP Family from Trimeresurus Stejnegeri Refined at 1.6 Angstroms Resolution: Structual relationship of the two domains
Function
[CRVP_TRIST] Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffein-stimulated contraction. May target voltage-gated calcium channels on smooth muscle (By similarity).
About this Structure
1rc9 is a 1 chain structure with sequence from Viridovipera stejnegeri. Full crystallographic information is available from OCA.
Reference
- Guo M, Teng M, Niu L, Liu Q, Huang Q, Hao Q. Crystal structure of the cysteine-rich secretory protein stecrisp reveals that the cysteine-rich domain has a K+ channel inhibitor-like fold. J Biol Chem. 2005 Apr 1;280(13):12405-12. Epub 2004 Dec 13. PMID:15596436 doi:10.1074/jbc.M413566200
