1ryw | pdb_00001ryw

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Template:STRUCTURE 1ryw

C115S MurA liganded with reaction products

Template:ABSTRACT PUBMED 15531591

Function

[MURA_ENTCL] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.

About this Structure

1ryw is a 8 chain structure with sequence from Enterobacter cloacae. Full crystallographic information is available from OCA.

See Also

Reference

  1. Eschenburg S, Priestman M, Schonbrunn E. Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release. J Biol Chem. 2005 Feb 4;280(5):3757-63. Epub 2004 Nov 5. PMID:15531591 doi:10.1074/jbc.M411325200

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OCA

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