1ud0 | pdb_00001ud0
From Proteopedia
CRYSTAL STRUCTURE OF THE C-TERMINAL 10-kDA SUBDOMAIN OF HSC70
Template:ABSTRACT PUBMED 12773536
Function
[HSP7C_RAT] Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex (By similarity).
About this Structure
1ud0 is a 4 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Chou CC, Forouhar F, Yeh YH, Shr HL, Wang C, Hsiao CD. Crystal structure of the C-terminal 10-kDa subdomain of Hsc70. J Biol Chem. 2003 Aug 8;278(32):30311-6. Epub 2003 May 28. PMID:12773536 doi:10.1074/jbc.M304563200
