1szu | pdb_00001szu

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Template:STRUCTURE 1szu

The structure of gamma-aminobutyrate aminotransferase mutant: V241A

Template:ABSTRACT PUBMED 15723541

Function

[GABT_ECOLI] Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semialdehyde (SSA).[1]

About this Structure

1szu is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Liu W, Peterson PE, Langston JA, Jin X, Zhou X, Fisher AJ, Toney MD. Kinetic and crystallographic analysis of active site mutants of Escherichia coli gamma-aminobutyrate aminotransferase. Biochemistry. 2005 Mar 1;44(8):2982-92. PMID:15723541 doi:https://dx.doi.org/10.1021/bi048657a
  1. ↑ Kurihara S, Kato K, Asada K, Kumagai H, Suzuki H. A putrescine-inducible pathway comprising PuuE-YneI in which gamma-aminobutyrate is degraded into succinate in Escherichia coli K-12. J Bacteriol. 2010 Sep;192(18):4582-91. doi: 10.1128/JB.00308-10. Epub 2010 Jul, 16. PMID:20639325 doi:https://dx.doi.org/10.1128/JB.00308-10

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