2c5f | pdb_00002c5f
From Proteopedia
TORPEDO CALIFORNICA ACETYLCHOLINESTERASE IN COMPLEX WITH A NON HYDROLYSABLE SUBSTRATE ANALOGUE, 4-OXO-N,N,N-TRIMETHYLPENTANAMINIUM
Template:ABSTRACT PUBMED 16763558
Function
[ACES_TORCA] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
About this Structure
2c5f is a 1 chain structure with sequence from Torpedo californica. Full crystallographic information is available from OCA.
See Also
Reference
- Colletier JP, Fournier D, Greenblatt HM, Stojan J, Sussman JL, Zaccai G, Silman I, Weik M. Structural insights into substrate traffic and inhibition in acetylcholinesterase. EMBO J. 2006 Jun 21;25(12):2746-56. Epub 2006 Jun 8. PMID:16763558
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Acetylcholinesterase
- Torpedo californica
- Colletier, J P.
- Fournier, D.
- Greenblatt, H M.
- Silman, I.
- Sussman, J L.
- Weik, M.
- Zaccai, G.
- Alpha/beta hydrolase
- Glycoprotein
- Gpi-anchor
- Hydrolase
- Lipoprotein
- Membrane
- Michaelis-menten complex
- Neurotransmitter cleavage
- Serine esterase
- Substrate hydrolysis
- Substrate inhibition
- Synapse
