2h2t | pdb_00002h2t

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Template:STRUCTURE 2h2t

CD23 Lectin domain, Calcium 2+-bound

Template:ABSTRACT PUBMED 16765898

Function

[FCER2_HUMAN] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).

About this Structure

2h2t is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Wurzburg BA, Tarchevskaya SS, Jardetzky TS. Structural changes in the lectin domain of CD23, the low-affinity IgE receptor, upon calcium binding. Structure. 2006 Jun;14(6):1049-58. PMID:16765898 doi:https://dx.doi.org/10.1016/j.str.2006.03.017

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