2ci1 | pdb_00002ci1
From Proteopedia
CRYSTAL STRUCTURE OF DIMETHYLARGININE DIMETHYLAMINOHYDROLASE I IN COMPLEX WITH S-NITROSO-LHOMOCYSTEINE
Function
[DDAH1_BOVIN] Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
About this Structure
2ci1 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Frey D, Braun O, Briand C, Vasak M, Grutter MG. Structure of the mammalian NOS regulator dimethylarginine dimethylaminohydrolase: A basis for the design of specific inhibitors. Structure. 2006 May;14(5):901-11. PMID:16698551 doi:https://dx.doi.org/10.1016/j.str.2006.03.006
