2cfo | pdb_00002cfo

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Template:STRUCTURE 2cfo

NON-DISCRIMINATING GLUTAMYL-TRNA SYNTHETASE FROM THERMOSYNECHOCOCCUS ELONGATUS IN COMPLEX WITH GLU

Template:ABSTRACT PUBMED 16876193

Function

[SYE_THEEB] Non-discriminating glutamyl-tRNA synthetase. Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). Acylates both tRNA(Glu) and tRNA(Gln) with glutamate, but has 13-fold higher efficiency with tRNA(Glu).[1]

About this Structure

2cfo is a 2 chain structure with sequence from Synechococcus elongatus. Full crystallographic information is available from OCA.

Reference

  1. Schulze JO, Masoumi A, Nickel D, Jahn M, Jahn D, Schubert WD, Heinz DW. Crystal structure of a non-discriminating glutamyl-tRNA synthetase. J Mol Biol. 2006 Sep 1;361(5):888-97. Epub 2006 Jul 5. PMID:16876193 doi:10.1016/j.jmb.2006.06.054
  1. Schulze JO, Masoumi A, Nickel D, Jahn M, Jahn D, Schubert WD, Heinz DW. Crystal structure of a non-discriminating glutamyl-tRNA synthetase. J Mol Biol. 2006 Sep 1;361(5):888-97. Epub 2006 Jul 5. PMID:16876193 doi:10.1016/j.jmb.2006.06.054

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