4kga | pdb_00004kga

Crystal structure of kallikrein-related peptidase 4

spinqualitylabelsall models 4kga, resolution 2.32Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4kga is a 2 chain structure. Full crystallographic information is available from OCA. Related: 2bdg, 2bdi, 2bdh, 4kel, 4k8y, 4k1e Activity: Glucokinase, with EC number 2.7.1.2 Disease [KLK4_HUMAN] Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) [MIM:204700]. AI2A1 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel. Function [KLK4_HUMAN] Involved in enamel formation.

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