3t3a | pdb_00003t3a

Crystal structure of H107R mutant of extracellular domain of mouse receptor NKR-P1A

spinqualitylabelsall models 3t3a, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3t3a is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: PO4 Related: 3m9z Gene: Klrb1a, Ly55, Ly55a, Nkrp1a (Mus musculus) Resources: FirstGlance, OCA, RCSB, PDBsum Publication Abstract from PubMed The structure of the H107R variant of the extracellular domain of the mouse natural killer cell receptor NKR-P1A has been determined by X-ray diffraction at 2.3 A resolution from a merohedrally twinned crystal. Unlike the structure of the wild-type receptor in space group I4(1)22 with a single chain per asymmetric unit, the crystals of the variant belonged to space group I4(1) with a dimer in the asymmetric unit. Different degrees of merohedral twinning were detected in five data sets collected from different crystals. The mutation does not have a significant impact on the overall structure, but led to the binding of an additional phosphate ion at the interface of the molecules. Structure of the H107R variant of the extracellular domain of mouse NKR-P1A at 2.3 A resolution.,Kolenko P, Rozbesky D, Vanek O, Bezouska K, Hasek J, Dohnalek J Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1519-23., Epub 2011 Nov 30. PMID:22139156 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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