Menin

<StructureSection load='4og6' size='340' side='right' caption='Structure of human menin complex with inhibitor (PDB code 4og6).' scene=>

Function

Menin (Men) is a putative tumor suppressor. Men possesses two functional nuclear localization signals and inhibits transcriptional activation by JunD.

3D structures of menin

Updated on 12-June-2014

3u84 – hMen – human
4og3, 4og4, 4og5, 4og6, 4og7, 4og8 – hMen + inhibitor
4gpq, 4gq3, 4gq4 – hMen (mutant) + inhibitor
4i80 – hMen + peptide inhibitor
3u85 – hMen + histone-lysine N-methyltransferase Mll peptide
4gq6 – hMen (mutant) + histone-lysine N-methyltransferase Mll peptide
3u86 – hMen + JunD peptide
3u85 – hMen + histone-lysine N-methyltransferase Mll + lens epithelium-derived growth factor

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky