4o6i | pdb_00004o6i

2.0A crystal structure of Lymphocytic Choriomeningitis Virus Nucleoprotein C-terminal Domain

spinqualitylabelsall models 4o6i, resolution 2.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4o6i is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: IMD, MG, ZN Related: 4o6h Resources: FirstGlance, OCA, RCSB, PDBsum Publication Abstract from PubMed The X-ray crystal structure of the Lymphocytic choriomeningitis virus nucleoprotein C-terminal immunosuppressive domain (LCMV NPDelta340) was determined to 2.0 A resolution. The structure indicates that LCMV NPDelta340, like the other structurally characterized arenaviral nucleoproteins, adopts the fold of an exonuclease. This structure provides a crucial three-dimensional template for functional exploration of the replication and immunosuppression of this prototypic arenavirus. Structure of the LCMV nucleoprotein provides a template for understanding arenavirus replication and immunosuppression.,West BR, Hastie KM, Saphire EO Acta Crystallogr D Biol Crystallogr. 2014 Jun;70(Pt 6):1764-9. doi:, 10.1107/S1399004714007883. Epub 2014 May 30. PMID:24914986 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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