CHEM2052 Tutorial Example4

CHEM2052_Tutorial_Example4

spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D This is a default text for your page CHEM2052 Tutorial Example4. Click above on edit this page to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia or to the article describing Jmol to the rescue. Function In later lecture we will look at an enzyme called Renin (also known as angiotensinase). The activity of this enzyme leads to elevation of blood pressure which can be beneficial in many settings. However if this process has become 'overactive' hypertension (high blood pressure) can result. Hypertension leads to cardiovascular disease which is the leading cause of death globally. The World Health Organisation states "An estimated 17.3 million people died from CVDs in 2008, representing 30% of all global deaths" see the following web page if you want to know more: Inibitors of Renin can be used to treat hypertension (high blood pressure). Renin Catalytic Residues Structural highlights This is a sample scene created with SAT to color by Group, and another to make a transparent representation of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

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Avril Robertson