Backbone representations

THIS ARTICLE IS UNDER DEVELOPMENT AND IS CURRENTLY INCOMPLETE. Eric Martz 20:18, 19 September 2014 (IDT)

Backbone representations are simplified 3D depictions of proteins or nucleic acids that enable the polymer chain structure to be seen. In proteins, a simple  backbone trace  connects alpha carbons (balls) but the  backbone trace line  does not coincide with any of the covalent bonds in the main chain (restore initial scene).

spinqualitylabelsall models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Protein Main Chain Lets begin with all atoms of a small alpha helix (15 amino acids) The atoms and bonds are colored by element: C H O N. First, we'll simplify by hiding the hydrogen atoms. Hydrogen atoms make up almost exactly 50% of the atoms in proteins. Next, we'll simplify by hiding the amino acid side chains. What remains is called the main chain. Each amino acid's main chain atoms are N-C-C, where the first C is the alpha carbon (shown as a ball), and the second, the carboxyl carbon with its double-bonded oxygen (double bonds not shown). We could also hide the oxygen atoms, leaving only the atoms that are part of the main chain, also called the backbone. Protein Backbone Trace Backbone Trace: Now we'll draw a  yellow line  between alpha carbons (balls). This line is called a  backbone trace . Hiding all atoms except alpha carbons makes the backbone trace even clearer. Here is the backbone trace by itself. Smoothed Protein Backbone Trace A smoothed backbone trace is another common backbone representation. Here, the  smoothed backbone trace is green . Here is the smoothed backbone trace alone. Ribbon Backbone Trace Perhaps the most common backbone representation is the ribbon. Here the  ribbon is violet , the standard secondary structure color for alpha helices. Here is the ribbon alone. Here the ribbon is decorated with thin lines for all atoms in this helix. Backbone Trace domain cartoon domain cartoon color structure domain cartoon + wireframe wireframe backbone backbone + trace trace

Proteopedia Page Contributors and Editors (what is this?)

Eric Martz, Margaret Franzen