1ftn | pdb_00001ftn

CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX

spinqualitylabelsall models 1ftn, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1ftn is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: GDP, MG Gene: SYNTHETIC HUMAN RHOA GENE (Homo sapiens) Resources: FirstGlance, OCA, RCSB, PDBsum Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 A resolution crystal structure of the human RhoA-GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding. Crystal structure of RhoA-GDP and its functional implications.,Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:9302995 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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