1ezj | pdb_00001ezj

From Proteopedia
Revision as of 09:02, 20 March 2008 by OCA (talk | contribs)
Jump to navigationJump to search


CRYSTAL STRUCTURE OF THE MULTIMERIZATION DOMAIN OF THE PHOSPHOPROTEIN FROM SENDAI VIRUS

File:1ezj.gif


Drag the structure with the mouse to rotate
1ezj, resolution 1.90Å
Ligands: EMC and CA
Activity: RNA-directed RNA polymerase, with EC number 2.7.7.48
Coordinates: save as pdb, mmCIF, xml



Overview

The high resolution X-ray structure of the Sendai virus oligomerization domain reveals a homotetrameric coiled coil structure with many details that are different from classic coiled coils with canonical hydrophobic heptad repeats. Alternatives to the classic knobs-into-holes packing lead to differences in supercoil pitch and diameter that allow water molecules inside the core. This open and more hydrophilic structure does not seem to be destabilized by mutations that would be expected to disrupt classic coiled coils.

About this Structure

1EZJ is a Single protein structure of sequence from Sendai virus. Full crystallographic information is available from OCA.

Reference

Tetrameric coiled coil domain of Sendai virus phosphoprotein., Tarbouriech N, Curran J, Ruigrok RW, Burmeister WP, Nat Struct Biol. 2000 Sep;7(9):777-81. PMID:10966649

Page seeded by OCA on Thu Mar 20 11:02:30 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA