1ytf | pdb_00001ytf

YEAST TFIIA/TBP/DNA COMPLEX

spinqualitylabelsall models 1ytf, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1ytf is a 6 chain structure with sequence from Saccharomyces cerevisiae. The July 2005 RCSB PDB Molecule of the Month feature on TATA-Binding Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2005_7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, RCSB, PDBsum Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed The X-ray crystal structure of the transcription factor IIA (TFIIA) in complex with the TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a four-helix bundle motif that together have a boot-like appearance. The beta-barrel extends the TBP beta-sheet and bridges over the DNA major groove immediately upstream of the TATA box. The four-helix bundle contributes substantially to the surface of the complex available for interaction with additional transcription factors. Crystal structure of a yeast TFIIA/TBP/DNA complex.,Tan S, Hunziker Y, Sargent DF, Richmond TJ Nature. 1996 May 9;381(6578):127-51. PMID:8610010 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also TATA-Binding Protein Transcription initiation factor

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