2g76 | pdb_00002g76

Crystal structure of human 3-phosphoglycerate dehydrogenase

spinqualitylabelsall models 2g76, resolution 1.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2g76 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: MLT, NAD Gene: PHGDH, PGDH3 (Homo sapiens) Activity: Phosphoglycerate dehydrogenase, with EC number 1.1.1.95 Resources: FirstGlance, OCA, RCSB, PDBsum Disease [SERA_HUMAN] Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:601815]. It is characterized by congenital microcephaly, psychomotor retardation, and seizures. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Phosphoglycerate dehydrogenase

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