Bacteriophage repressor

<StructureSection load='1per' size='350' side='right' caption='Structure o phage 434 repressor cI protein complex with DNA (PDB entry 1per)' scene=>

The bacteriophage repressor controls the genetic switch determining the lytic cycle following phage infection. It competes with the Cro protein which selects for the lysogenic cycle. For details see Lambda repressor.

3D structures of bacteriophage repressor

Updated on 18-November-2014

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• Lambda repressor (LR)
  • 1lrp – LR – Enterobacteria phage λ
    
  • 2hnf, 2ho0 – LR (mutant)
    
  • 1lmb, 1lli – LR + DNA
    
• Lambda repressor cI protein
  • 1f39, 1kca – LR C terminal
    
  • 3kz3 – LR (mutant)
    
  • 3bdn – LR (mutant) + DNA
    
  • 1rio – LR N terminal + σ factor + DNA
    
• Lambda repressor Cro protein
  • 4cro, 5cro – LR N terminal
    
  • 1orc, 1d1m, 1d1l, 2ecs, 2ovg – LR N terminal (mutant)
    
  • 1cop – LR N terminal - NMR
    
  • 2orc, 2a63 – LR N terminal (mutant) - NMR
    
  • 6cro, 3orc – LR N terminal + DNA
    
• Phage 434 repressor cI protein (434R)
  • 1pra, 1r63, 2r63, 1sq8 – 434R N terminal - NMR
    
  • 1r69 – 434R N terminal
    
  • 2or1, 1per, 1rpe – 434R N terminal + DNA
    
• Phage 434 repressor Cro protein (434R)
  • 2cro – 434R
    
  • 1zug – 434R N terminal - NMR
    
  • 3cro – 434R N terminal + DNA
    
• Mu bacteriophage repressor (MR)
  • 1qpm – MR N terminal – NMR
    
  • 1g4d – MR N terminal + DNA – NMR
    
• 186 bacteriophage repressor cI protein (186R)
  • 2fjr – 186R (mutant)
    
  • 2fkd – 186R C terminal
    
• P22 bacteriophage repressor (P22R)
  • 1rzs – P22R N terminal – NMR
    

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Michal Harel, Alexander Berchansky