3gdd | pdb_00003gdd

An inverted anthraquinone-DNA crystal structure

spinqualitylabelsall models 3gdd, resolution 2.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3gdd is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 5BD, MG NonStd Res: BRU Resources: FirstGlance, OCA, RCSB, PDBsum Publication Abstract from PubMed The crystal structure of the telomeric sequence d(UBrAGG) interacting with an anthraquinone derivative has been solved by MAD. In all previously studied complexes of intercalating drugs, the drug is usually sandwiched between two DNA base pairs. Instead, the present structure looks like a crystal of stacked anthraquinone molecules in which isolated base pairs are intercalated. Unusual base pairs are present in the structure, such as G.G and A.UBr reverse Watson-Crick base pairs. Structure of a stacked anthraquinone-DNA complex.,De Luchi D, Uson I, Wright G, Gouyette C, Subirana JA Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt, 9):1019-22. Epub 2010 Aug 21. PMID:20823516 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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