4fgt | pdb_00004fgt
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Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes inactive conformation of the enzyme.
spin
quality
labels
all models
4fgt
,
resolution
2.00Å
Show:
Asymmetric Unit
Biological Assembly
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Structural highlights
4fgt
is a 2 chain structure with sequence from
Homo sapiens
. Full crystallographic information is available from
OCA
. For a
guided tour on the structure components
use
FirstGlance
.
Ligands:
SO4
NonStd Res:
CME
Related:
3n5e
,
3egy
Gene:
TYMS, TS, OK/SW-cl.29 (
Homo sapiens
)
Activity:
Thymidylate synthase
, with EC number
2.1.1.45
Resources:
FirstGlance
,
OCA
,
RCSB
,
PDBsum
See Also
Thymidylate synthase
Contents
1
Structural highlights
2
See Also
Proteopedia Page Contributors and Editors
(
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)
OCA
proteopedia link
Categories
:
Homo sapiens
Thymidylate synthase
Costi, M P
Finer-Moore, J
Stroud, R M
Tochowicz, A
Dimer
Hts complex with peptidic inhibitor
Inactive hts conformation
Mutant k47a of ht
Transferase-transferase inhibitor complex
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