4ai3 | pdb_00004ai3

Flo5A showing a heptanuclear gadolinium cluster on its surface after 60 min of soaking

spinqualitylabelsall models 4ai3, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4ai3 is a 1 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CL, GD, GOL Related: 2xjr, 2xju, 2xjv, 2xjt, 2xjq, 2xjp, 2xjs, 4ahx, 4ai1, 4ai0, 4ahy, 4ai2, 4ahz, 4ahw Resources: FirstGlance, OCA, RCSB, PDBsum Publication Abstract from PubMed Protein-bound contrast: The unusual observation of a heptanuclear gadolinium-oxo cluster on the surface of the cell-adhesion protein Flo5A establishes the basis for directed incorporation of poly-lanthanide clusters into biomolecules. The observed gadolinium cluster might serve as a paradigm for the design of protein-based MRI contrast agents. Complex Gadolinium-Oxo Clusters Formed along Concave Protein Surfaces.,Veelders M, Essen LO Chembiochem. 2012 Aug 31. doi: 10.1002/cbic.201200441. PMID:22936626 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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