Template:STRUCTURE 2ev9
Shikimate dehydrogenase (AroE) catalyzes the conversion of shikimate and NADP+ to 3-dihydroshikimate, NADPH and H+. It is part of the shikimate pathway which is responsible for the biosynthesis of phenylalanine, tyrosine and tryptophan. This pathway is found in bacteria, fungi, plants, algae and parasites and is missing in animals and humans.
3D Structures of shikimate dehydrogenase
Updated on 10-December-2014
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- Shikimate dehydrogenase
- 1p74, 1p77 – AroE – Haemophilus influenzae
- 1wxd – TtAroE – Thermus thermophilus
- 2hk7, 2hk8 – AaAroE – Aquifex aeolicus
- 2egg – AroE – Geobacillus kaustophilus
- 3fbt – AroE/chorismate mutase – Clostridium acetobutylicum
- 3don – SeAroE – Staphylococcus epidermidis
- 3o8q – VcAroE – Vibrio cholerae
- 3pwz – AroE 3 – Pseudomonas putida
- 3phg – HpAroE – Helicobacter pylori
- 4foo, 4fpx – HpAroE (mutant)
- 3u62 – AroE – Thermotoga maritima
- 2nlo – CgAroE – Corynebacterium glutamicum
- Shikimate dehydrogenase complex with NADP
- 1nyt, 1vi2 – EcAroE + NADP – Escherichia coli
- 1nvt – MjAroE + NADP – Methanocaldococcus jannaschii
- 2cy0 – TtAroE + NADP
- 3toz – LmAroE + NAD – Listeria monocytogenes
- 3t4e – AroE + NAD – Salmonella enterica
- 3jyo - CgAroE + NAD
- Shikimate dehydrogenase complex with shikimate
- 2d5c – TtAroE + shikimate
- 3doo – SeAroE + shikimate
- 3pgj – VcAroE + shikimate
- 3phh – HpAroE + shikimate
- 4fos, 4fq8, 4fr5, 4fsh – HpAroE (mutant) + shikimate
- 3phj – HpAroE + 3-dihydroshikimate
- Shikimate dehydrogenase complex with NADP and shikimate
- 2ev9 – TtAroE + shikimate + NADP
- 2hk9 – AaAroE + shikimate + NADP
- 3sef – VcAroE + shikimate + NADP
- 3tnl – LmAroE + shikimate + NAD
- 3phi – HpAroE + shikimate + NADP
- 3jyp - CgAroE + quinate + NAD
- 3jyq - CgAroE + shikimate + NAD
