Sandbox CYPMetabolism

<StructureSection load='2hi4' size='500' frame='true' side='right' caption= scene= pspeed='8'>

Heme

Fe/S Bond

𝛂-naphthoflavone orientation

flavone vDW forces

flavone inside binding pocket

isosurface of flavone with wireframe residues

3A4

Binding pocket without Ery

Binding pocket with Ery

Ketoconazole bound to CYP3A4

Ketoconazole without CYP

Keto pocket opaque

Keto pocket translucent

Ritonavir

cavity

Thiazole ring bound to heme