3plt | pdb_00003plt

Crystal structure of Lsp1 from Saccharomyces cerevisiae

spinqualitylabelsall models 3plt, resolution 2.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3plt is a 3 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 3kq1 Gene: LSP1, YPL004C (Saccharomyces cerevisiae) Resources: FirstGlance, OCA, RCSB, PDBsum Publication Abstract from PubMed Plasma membranes are organized into domains of different protein and lipid composition. Eisosomes are key complexes for yeast plasma membrane organization, containing primarily Pil1 and Lsp1. Here we show that both proteins consist mostly of a banana-shaped BAR domain common to membrane sculpting proteins, most similar to the ones of amphiphysin, arfaptin 2 and endophilin 2. Our data reveal a previously unrecognized family of BAR-domain proteins involved in plasma membrane organization. Eisosome-driven plasma membrane organization is mediated by BAR domains.,Ziolkowska NE, Karotki L, Rehman M, Huiskonen JT, Walther TC Nat Struct Mol Biol. 2011 Jun 19. doi: 10.1038/nsmb.2080. PMID:21685922 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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