1gio | pdb_00001gio

NMR SOLUTION STRUCTURE OF BOVINE ANGIOGENIN, 10 STRUCTURES

spinqualitylabelsall models 1gio, 10 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1gio is a 1 chain structure with sequence from Bos taurus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, RCSB, PDBsum Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed The three-dimensional structure of bovine angiogenin has been determined using two- and three-dimensional proton NMR spectroscopy. The solution structure is very close to that recently determined by X-ray diffraction analysis. This structure appears well defined, even if five loops and one helix exhibit greater flexibility. Analysis of the active site geometry confirms the position of the Glu-118 residue which obstructs the pyrimidine binding site. There is no experimental evidence of an unobstructed conformation of angiogenin in solution. In addition, it appears that the Glu-118 and Ser-119 residues and the cell receptor binding loop may play an important role in the differences of C-terminal fragment organization and ribonucleolytic activity observed between angiogenins and ribonuclease A. Solution structure of bovine angiogenin by 1H nuclear magnetic resonance spectroscopy.,Lequin O, Albaret C, Bontems F, Spik G, Lallemand JY Biochemistry. 1996 Jul 9;35(27):8870-80. PMID:8688423 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also User:Jaime.Prilusky/Test/tree

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