4fhq | pdb_00004fhq

Crystal Structure of HVEM

spinqualitylabelsall models 4fhq, resolution 2.25Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4fhq is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 2aw2, 1jma Gene: HVEA, HVEM, TNFRSF14, UNQ329/PRO509 (Homo sapiens) Resources: FirstGlance, OCA, RCSB, PDBsum Function [TNR14_HUMAN] Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.

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