3epp | pdb_00003epp

Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin

spinqualitylabelsall models 3epp, resolution 2.41Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3epp is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: SFG Related: 3bgv Gene: RNMT, KIAA0398 (Homo sapiens) Activity: mRNA (guanine-N(7)-)-methyltransferase, with EC number 2.1.1.56 Resources: FirstGlance, OCA, RCSB, PDBsum Function [MCES_HUMAN] mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Proteopedia Page Contributors and Editors (what is this?)

OCA