3k7e | pdb_00003k7e

Crystal structure of human ligand-free mature caspase-6

spinqualitylabelsall models 3k7e, resolution 3.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3k7e is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 1cp3 Gene: CASP6, MCH2 (Homo sapiens) Activity: Caspase-6, with EC number 3.4.22.59 Resources: FirstGlance, OCA, RCSB, PDBsum Function [CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. See Also Caspase Caspase-6 and neurodegeneration Molecular Playground/Caspase-6 and neurodegeneration User:Kevin Buadlart Dagbay

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