3tbg | pdb_00003tbg

Human cytochrome P450 2D6 with two thioridazines bound in active site

spinqualitylabelsall models 3tbg, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3tbg is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: GOL, HEM, PO4, RTZ, ZN Related: 3qm4 Gene: CYP2D6, CYP2DL1 (Homo sapiens) Activity: Unspecific monooxygenase, with EC number 1.14.14.1 Resources: FirstGlance, OCA, RCSB, PDBsum Function [CP2D6_HUMAN] Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. See Also Cytochrome P450

Proteopedia Page Contributors and Editors (what is this?)

OCA