1yho | pdb_00001yho
From Proteopedia
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| 1yho | |||||||||||||
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| Ligands: | NDP and TRR | ||||||||||||
| Activity: | Dihydrofolate reductase, with EC number 1.5.1.3 | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures
Disease
Known disease associated with this structure: Anemia, megaloblastic, due to DHFR deficiency (1) OMIM:[126060]
About this Structure
1YHO is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH., Kovalevskaya NV, Smurnyy YD, Polshakov VI, Birdsall B, Bradbury AF, Frenkiel T, Feeney J, J Biomol NMR. 2005 Sep;33(1):69-72. PMID:16222560
Page seeded by OCA on Thu Mar 20 15:22:59 2008
