3dws | pdb_00003dws

Leishmania major Coproporphyrinogen III Oxidase with bound ligand

spinqualitylabelsall models 3dws, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3dws is a 2 chain structure with sequence from Leishmania major. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: ACT, FIC NonStd Res: MSE Related: 2qt8, 3dwr, 1vju Gene: LMAJ006828, LmjF06.1270 (Leishmania major) Activity: Coproporphyrinogen oxidase, with EC number 1.3.3.3 Resources: FirstGlance, OCA, RCSB, PDBsum Function [HEM6_LEIMA] Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (By similarity).[HAMAP-Rule:MF_00333] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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