Structural highlights
3wgu is a 6 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | ADP, ALF, CLR, MG, NA, NAG, PC1 |
| Related: | 2zxe, 2zbd, 3wgv |
| Activity: | Sodium/potassium-exchanging ATPase, with EC number 3.6.3.9 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[AT1B1_PIG] This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
