4i13 | pdb_00004i13

Nanobody ca1697 binding to the DHFR.folate binary complex

spinqualitylabelsall models 4i13, resolution 1.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4i13 is a 2 chain structure with sequence from Camelus glama and Ecoli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: FOL Related: 4i1n Gene: folA, tmrA, b0048, JW0047 (ECOLI) Activity: Dihydrofolate reductase, with EC number 1.5.1.3 Resources: FirstGlance, OCA, RCSB, PDBsum Function [DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. See Also Dihydrofolate reductase

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