4di5 | pdb_00004di5

Co-crystal structure of WT 5-epi-Aristolochene synthase from Nicotiana tobaccum with geraniline

spinqualitylabelsall models 4di5, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4di5 is a 1 chain structure with sequence from Nicotiana tabacum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 1GA, ACT, DPO, MG Gene: 5-EAS, EAS3, EAS4 (Nicotiana tabacum) Activity: 5-epiaristolochene synthase, with EC number 4.2.3.61 Resources: FirstGlance, OCA, RCSB, PDBsum Function [5EAS_TOBAC] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.

Proteopedia Page Contributors and Editors (what is this?)

OCA