Structural highlights
4er0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | AW1, UNX |
| Related: | 4eqz, 4er3, 4er5, 4er6, 4er7 |
| Gene: | DOT1L, KIAA1814, KMT4 (Homo sapiens) |
| Activity: | Histone-lysine N-methyltransferase, with EC number 2.1.1.43 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[DOT1L_HUMAN] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
See Also
